| 摘要 |
Currently used techniques for sealing impaired tissue following medical procedures are not optimal. Manual compression, though effective, is time consuming and current sealing products use animal proteins, which can cause immunological reactions and disease. Therefore, a desirable product is one that easily and effectively seals a wound in tissue without side effects. Lipids that adhere to tissue and expand in size when applied are well suited for use as a biosealant device. Lipids, which are solid at sub-physiological temperature and exhibit a phase change at or about physiological temperature to adhere and expand within the wound are desirable for use in a biosealant device. One such class of lipid that is naturally well suited for this use are cubic phase forming monoglycerides. However, other lipids in their natural or modified states can also be used.
|
