发明名称 Highly bioavailable oral delayed release dosage forms of O-desmethylvenlafaxine succinate
摘要 An oral, highly bioavailable unit dosage form of O-desmethylvenlafaxine succinate (DVS) having a delayed release of at least about one hour and a sustained release over multiple hours to provide a total release of greater than about 85% within about 12 to about 14 hours is described. In one embodiment, the superbioavailable DVS composition has a delayed release of about two hours and a total release of greater than about 95% within about 12 to about 14 hours. Use of the formulation in treating depression and reducing the gastrointestinal side-effects of O-desmethylvenlafaxine (ODV) is also described.
申请公布号 US2007014859(A1) 申请公布日期 2007.01.18
申请号 US20060486324 申请日期 2006.07.13
申请人 WYETH 发明人 SHAH SYED M.;FAWZI MAHDI B.;DIORIO CHRISTOPHER R.
分类号 A61K9/22;A61K9/26 主分类号 A61K9/22
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