发明名称 Amino nicotinate derivatives as glucokinase (GLK) modulators
摘要 The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.
申请公布号 US7160906(B2) 申请公布日期 2007.01.09
申请号 US20040482572 申请日期 2004.06.01
申请人 ASTRAZENECA AB 发明人 HAYTER BARRY RAYMOND;CURRIE GORDON STUART;HARGREAVES RODNEY BRIAN;JAMES ROGER;JONES CLIFFORD DAVID;MCKERRECHER DARREN;ALLEN JOANNE VICTORIA;CAULKETT PETER WILLIAM RODNEY;JOHNSTONE CRAIG;GASKIN HAROLD
分类号 A61K31/44;A61K31/443;A61K31/4436;A61K31/4439;A61K31/455;A61K31/496;A61K31/506;A61K31/5377;A61P3/04;A61P3/10;A61P43/00;C07D213/75;C07D213/80;C07D401/12;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14 主分类号 A61K31/44
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