发明名称 INDOLYL-3-GLYOXYLIC ACID DERIVATIVES WITH ANTITUMORAL ACTIVITY
摘要 The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agentsand to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if appropriate also in the form of the physiologically tolerable acid addition salts or N-oxides. Furthermore, the invention also includes antitumor agents comprising as active compound one or more N-substituted indole-3-glyoxylamides according to the general formula 1 and, if appropriate, their physiologically tolerable acid addition salts and, if possible, N-oxides and a pharmaceutically utilizable carrier and/or diluent or auxiliary substance in the form of tablets, coated tablets, capsules, solutions for infusion or ampoules, suppositories, patches, powder preparations which can be employed by inhalation, suspensions, creams and ointments.
申请公布号 PL192779(B1) 申请公布日期 2006.12.29
申请号 PL19990343525 申请日期 1999.03.22
申请人 ASTA MEDICA AG 发明人 NICKEL BERND;SZELENYI ISTVAN;SCHMIDT JUERGEN;EMIG PETER;REICHERT DIETMAR;GUENTHER ECKHARD;BRUNE KAY
分类号 A61K31/4439;C07D401/06;A61K31/403;A61K31/404;A61K31/4178;A61K31/4427;A61K31/444;A61K31/454;A61K31/4545;A61K31/4709;A61K31/496;A61P35/00;A61P35/02;A61P35/04;C07D209/18;C07D401/12;C07D401/14 主分类号 A61K31/4439
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