THIAZOLE DERIVATIVE

摘要

It is intended to provide an adenosine A_2A receptor antagonist containing as an active ingredient a thiazole derivative represented by the general formula (I) [in the formula, R¹ represents a substituted or unsubstituted five-membered aromatic heterocyclic group containing at least one oxygen atom, R² represents a substituted or unsubstituted heterocyclic group, -COR⁶ (in the formula, R⁶ represents a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted aromatic heterocyclic group or the like) or the like, R³ represents the general formula (II), -NHCOR⁷ (in the formula, R⁷ represents -NR⁸R⁹ or the like) or the like], or a pharmacologically acceptable salt thereof, etc. (I) (II)