发明名称 |
SUBSTITUTED PYRR0LIDIN-2-0NES , PIPERIDIN-2-0NES AND ISOTHIAZOLIDINE-1, 1-DIOXIDES, THEIR USE AS KVl .5 POTASSIUM CHANNEL BLOCKERS AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM |
摘要 |
<p>The invention relates to compounds of the formula (I), in which A, R1 , R2, R3, R4, R5, R6, R7 and n have the meanings stated in the claims. The compounds are particularly suitable as antiarrhythmic active ingredients, in particular for the treatment and prophylaxis of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.</p> |
申请公布号 |
WO2006136305(A1) |
申请公布日期 |
2006.12.28 |
申请号 |
WO2006EP05579 |
申请日期 |
2006.06.10 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH;BRENDEL, JOACHIM;ENGLERT, HEINRICH CHRISTIAN;PEUKERT, STEFAN;WIRTH, KLAUS;WAGNER, MICHAEL;RUXER, JEAN-MARIE;PILORGE, FABIENNE |
发明人 |
BRENDEL, JOACHIM;ENGLERT, HEINRICH CHRISTIAN;PEUKERT, STEFAN;WIRTH, KLAUS;WAGNER, MICHAEL;RUXER, JEAN-MARIE;PILORGE, FABIENNE |
分类号 |
C07D401/06;A61K31/4015;A61K31/4412;A61P9/00;A61P11/00;A61P25/28;A61P35/00;C07D207/26;C07D211/76;C07D275/02;C07D401/14;C07D409/06 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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