发明名称 |
Method for analysis of compounds with amino group and analytical reagent therefor |
摘要 |
The present invention provides a method for the analysis of a compound with amino group (e.g., an amino acid or peptide) contained in a sample and convenient manner with a high sensitivity. The compound with amino group in a sample containing the compound with amino group is labeled with a specific carbamate compound such as p-trimethylammonium anilyl-N-hydroxysuccinimidyl carbamate iodide to enhance the selectivity and sensitivity. The present invention is preferably used in conjunction with mass spectrometry such as MS/MS method to facilitate quantitative analysis. The present invention further provides labeling reagents for mass spectrometry.
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申请公布号 |
US7148069(B2) |
申请公布日期 |
2006.12.12 |
申请号 |
US20040918380 |
申请日期 |
2004.08.16 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
MIYANO HIROSHI;YAHASHI AKIHISA;SHIMBO KAZUTAKA;NAKAZAWA MASAKAZU;HIRAYAMA KAZUO |
分类号 |
G01N33/00;C07D215/38;G01N24/00;G01N33/68 |
主分类号 |
G01N33/00 |
代理机构 |
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