发明名称 |
GEMCITABINE DERIVATIVES |
摘要 |
The invention provides Gemcitabine esters or amides in which the 3'- and/or 5'- OH group and/or the N4-amino group is derivatised with a C18- and/or C20- saturated or mono-unsaturated aryl group, preferably an acyl group selected from oleoyl, elaidoyl, cis-icosenoyl and trans-eicosenoyl. The Gemcitabine esters and amides are useful as anti- cancer and anti-viral agents. |
申请公布号 |
CA2278056(C) |
申请公布日期 |
2006.12.12 |
申请号 |
CA19982278056 |
申请日期 |
1998.01.23 |
申请人 |
NORSK HYDRO ASA |
发明人 |
MYHREN, FINN;BORRETZEN, BERNT;SANDVOLD, MARIT LILAND;DALEN, ARE |
分类号 |
C07H19/073;A61K31/70;A61K31/7068;A61P31/12;A61P35/00;C07H1/00;C07H19/06 |
主分类号 |
C07H19/073 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|