| 发明名称 |
Hetero-bridge substituted 8-arylquinoline pde4 inhibitors |
| 摘要 |
8-arylquinolines wherein the aryl group at the 8-position contains a meta one or two atom bridge to a phenyl, 5 or 6 member heteroaryl or fused bicyclic heteroaryl group, and wherein at least one of the bridge atoms is not carbon, are PDE4 inhibitors.
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| 申请公布号 |
US7144896(B2) |
申请公布日期 |
2006.12.05 |
| 申请号 |
US20040508261 |
申请日期 |
2004.09.17 |
| 申请人 |
MERCK FROSST CANADA LTD. |
发明人 |
GALLANT MICHEL;DESCHENES DENIS;DUBE DANIEL;DUBE LAURENCE;LACOMBE PATRICK;MACDONALD DWIGHT |
| 分类号 |
C07D215/04;A61K31/47;A61K31/4709;A61K31/5377;A61P11/00;A61P25/00;C07D215/12;C07D215/14;C07D401/06;C07D401/12;C07D401/14;C07D409/12;C07D409/14;C07D413/02;C07D413/12;C07D417/02;C07D417/12;C07D487/04 |
主分类号 |
C07D215/04 |
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