MODIFIED-RELEASE COMPOSITION OF AT LEAST ONE FORM OF VENLAFAXINE

摘要

The present invention relates to a modified release composition of at least one form of venlafaxine, which is a delayed controlled release composition. The composition comprises a core comprising at least one form of venlafaxine selected from t he group consisting of venlafaxine, an active metabolite of venlafaxine, a pharmaceutically acceptable salt of venlafaxine, a pharmaceutically acceptable salt of an active metabolite of venlafaxine, and combinations thereof, less than 10% of a gelling agent and a pharmaceutically acceptable excipient. The composition further compris es a modified release coating which substantially surrounds the core which provid es a delayed controlled release of the at least one form of venlafaxine.