REMEDY, TREATMENT METHOD AND CYTOSTATIC AGENT FOR PRE-B CELL ACUTE LYMPHATIC LEUKEMIA, MODEL MOUSE OF PRE-B CELL ACUTE LYMPHATIC LEUKEMIA AND PRE-B CELL LEUKEMIA CELL STRAIN

摘要

PROBLEM TO BE SOLVED: To obtain a cytostatic agent against pre-B cell acute lymphatic leukemia cells and a leukemia remedy for treating a leukemic patient caused by pre-B cell acute lymphatic leukemia cells and to provide a treatment method.

SOLUTION: A leukemic patient caused by pre-B cell acute lymphatic leukemia cells is treated by administration of a leukemia remedy being a cytostatic agent that reduces activity of an STAT5 (signal transducer and activator of transcription 5) signal transmission system in pre-B cell acute lymphatic leukemia cells or a leukemia remedy being a cytostatic agent that enhances activity of a BASH (B cell-restricted adaptor) signal transmission system to a leukemic patient caused by pre-B cell acute lymphatic leukemia cells having reduced activity of a BASH signal transmission system and an activated STAT5 signal transmission system.

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