摘要 |
A drug having a high affinity for benzodiazepine É 3 receptors and showing curative and preventive effects for anxiety and depression, which comprises as the active ingredient, for example, a compound of the formula (1):
wherein R 1 and R 2 are independently a hydrogen atom, an optionally substituted alkyl group, an optionally substituted aryl group, etc.,
R 3 and R 4 are independently a hydrogen atom, an optionally substituted alkyl group, etc.,
R 5 , R 6 , R 7 and R 8 are independently a hydrogen atom, an optionally substituted alkyl group, an optionally substituted aryl group, etc.,
X is an oxygen atom, a sulfur atom, NR 10 , etc. (in which R 10 is a hydrogen atom, an optionally substituted alkyl group, etc.)
|
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD. |
发明人 |
KODO, TORU;FUKAYA, TAKAYUKI;KOYAMA, KOJI;MASUMOTO, SHUJI;FUJIBAYASHI, NAO |