发明名称 IMMUNE CONJUGATE
摘要 PROBLEM TO BE SOLVED: To provide an immune conjugate of a new fused protein for delivering a ligand having bioactivity to a specific target cell or tissue that can be used for, for example, treating tumors. SOLUTION: The fused protein, to which the present invention relates, comprises a monoclonal antibody or its fragment that recognizes a tumor-related target element, preferably a molecule preferentially expressed on human tumor cells such as a human epidermal growth factor receptor (EGFR), and a ligand having bioactivity such as a growth and/or differentiation factor. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2006298936(A) 申请公布日期 2006.11.02
申请号 JP20060178409 申请日期 2006.06.28
申请人 MERCK PATENT GMBH 发明人 VON HOEGEN ILKA;HOFFMANN UWE;JAEGGLE CARLOTA-SILVIA;STRITTMATTER WOLFGANG;STADLMUELLER JOERG;MATZKU SIEGFRIED
分类号 C07K19/00;C12N15/09;A61K;A61K38/00;A61K38/16;A61K38/18;A61K38/19;A61K38/20;A61K39/00;A61K39/295;A61K39/395;A61K39/44;A61K47/48;A61P35/00;A61P35/04;C07K;C07K14/52;C07K14/525;C07K14/54;C07K14/55;C07K16/00;C07K16/28;C07K16/30;C07K16/42;C07K16/46;C12N;C12N15/13;C12N15/19;C12N15/55;C12N15/62;C12N15/64;C12N15/72;C12N15/79;C12P21/02;C12P21/08;C12R1/19;C12R1/91 主分类号 C07K19/00
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