发明名称 |
Synthesis of 5-Azacytidine |
摘要 |
The present invention provides a method for the preparation of 5-azacytidine, wherein 5-azacytidine is represented by the structure: The method involves the silylation of 5-azacytosine, followed by the coupling of silylated 5-azacytosine to a protected beta-D-ribofuranose derivative. The coupling reaction is catalyzed by trimethylsilyl trifluoromethanesulfonate (TMS-Triflate).
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申请公布号 |
US2006247432(A1) |
申请公布日期 |
2006.11.02 |
申请号 |
US20060381275 |
申请日期 |
2006.05.02 |
申请人 |
IONESCU DUMITRU;BLUMBERGS PETER |
发明人 |
IONESCU DUMITRU;BLUMBERGS PETER |
分类号 |
C07H19/048;A61K;A61K31/70;C07H19/00;C07H19/056;C07H19/12 |
主分类号 |
C07H19/048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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