发明名称 |
Long lasting insulin derivatives and methods thereof |
摘要 |
The present invention relates to an insulin derivative comprising an insulin molecule and a reactive group for covalently bonding a blood component, wherein preferably the insulin molecule is human natural insulin molecule and the reactive group is coupled to an amino acid of the insulin molecule at a position selected from the positions Gly A1, Phe B1 and Lys B29.
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申请公布号 |
US2006241019(A1) |
申请公布日期 |
2006.10.26 |
申请号 |
US20040565900 |
申请日期 |
2004.07.26 |
申请人 |
BRIDON DOMINIQUE P;CASTAIGNE JEAN-PAUL;HUANG XICAI;LEGER ROGER;ROBITAILLE MARTIN |
发明人 |
BRIDON DOMINIQUE P.;CASTAIGNE JEAN-PAUL;HUANG XICAI;LEGER ROGER;ROBITAILLE MARTIN |
分类号 |
A61K38/28;A61K38/00;A61K47/48;A61P3/10;A61P5/50;C07K14/62 |
主分类号 |
A61K38/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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