| 摘要 |
The invention relates to the processing of a biological sample for histological analysis. In particular, it relates to a rapid automated processing system that can be operated with continuous throughput and that eliminates the use of toxic solvents such as xylene. Provided is a method for processing a biological sample for histological analysis, comprising contacting the sample with a composition comprising a supercritical or near supercritical fluid followed by impregnating the sample under a pressure of more than 1 bar with an embedding medium, preferably paraffin. Also provided is a processor ( 1 ) for preparing at least one sample ( 10 ) for histological analysis, comprising at least one process reactor ( 9 ) for the at least one sample ( 10 ), characterized in that the processor ( 1 ) comprises supplying means ( 4 ) for supplying to the reactor ( 9 ) at least one substance of which at least one is in supercritical phase or near supercritical phase and at least one supplying means ( 7 ) for adding the embedding medium to the reactor ( 9 ) through conduit ( 8 ).
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