COMPOSITIONS AND METHODS RELATED TO MODIFIED RETROVIRAL VECTORS FOR RESTRICTED, SITE SPECIFIC INTEGRATION

摘要

Embodiments of the invention include compositions comprising and methods utilizing a retroviral integrase complex comprising a recombinant integrase having a domain comprising a non-native protein binding site, and a DNA binding protein comprising a DNA binding domain and a peptide binding domain that binds the non­native protein binding site of the recombinant integrase.