| 摘要 |
Biological molecules such as protein molecules are ionized without being damaged. Massive cluster ions of a water/methanol mixture (to which acetic acid or ammonia, etc., has been added) (in the vicinity of dry ice-acetone temperature) are generated in a charged-droplet generating chamber 31 by a cold electrospray 32 , and the ions are accelerated in an evacuated acceleration chamber 41 by a high-voltage electric field on the order of 10 KV, thereby bombarding a biological sample thin film, which has been applied to a cooled specimen substrate, and achieving ionization of large biomolecules.
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