发明名称 Methods for the diagnosis, prognosis and treatment of metabolic syndrome
摘要 The present invention provides methods for detecting susceptibility to metabolic syndrome. In particular, the presence of differences in at least one of the following genes; microsomal triglyceride transfer protein (MTP), fatty acid binding protein 2 (FABP2), annexin A5 (ANXA5), pyruvate dehydrogenase (lipoamide) alpha 2 (PDHA2), CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (CDS 1), and glycerol kinase 2 (GK2) serves as a prognostic and diagnostic indicator of metabolic syndrome. Furthermore, metabolic syndrome can be treated by regulating the levels of MTP, FABP2, ANXA5, PDHA2, CDS1, and GK2.
申请公布号 US2006211020(A1) 申请公布日期 2006.09.21
申请号 US20060359346 申请日期 2006.02.22
申请人 THE TRUSTEES OF BOSTON UNIVERSITY 发明人 FARRER LINDSAY A.;WYSZYNSKI DIEGO F.
分类号 C12Q1/68;A61B;A61K38/16;A61K38/17;A61K39/395;A61K48/00;C07H21/04;G01N33/50 主分类号 C12Q1/68
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