发明名称 2-CYANOPYRROLIDINECARBOXAMIDS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS
摘要 A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X1 and X 2 each is independently lower alkylene; X3 is = CH2, =CHF or =CF2; R1 is substituent, R2 and R3 each is independently H or lower alkyl; n is 0, 1, 2, 3 or 4.] having the activity inhibiting DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.
申请公布号 KR20060100390(A) 申请公布日期 2006.09.20
申请号 KR20067007974 申请日期 2006.04.25
申请人 ASTELLAS PHARMA INC. 发明人 SHIMA ICHIRO;KURODA AKIO;OHKAWA TAKEHIKO;KUROSAKI TOSHIO;SAWADA YUKI;WADA AIKO
分类号 C07D401/06;A61K31/4025;C07D401/12;C07D401/14;C07D403/06;C07D405/12;C07D409/12;C07D451/04;C07D453/02;C07D471/08;C07D487/08 主分类号 C07D401/06
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