发明名称 Bacteria strain inducing a reduction in the expression of Rbx1
摘要 <p>The observed gene expression level in the presence of bacteria is compared with the control culture in the absence of the bacteria and the selection of bacteria in the observed level is 4 times lower than the observed control culture. The cells are incubated for 16 hours in the presence of 10-10 3>u.f.c (colone forming units) bacterial by the cell. The level of the gene expression is determined by evaluating the quantity of transcribed gene/measuring the protein rbx-1, which is expressed by the cells and the process further comprises implementing and culturing the selected bacteria. Screening for bacteria with anti-inflammatory properties comprising incubating an epithelial cell culture, determining rbx-1 gene expression level, comparing the observed level and selecting the bacteria in the presence of the observed level. The observed gene expression level in the presence of bacteria is compared with the control culture in the absence of the bacteria and the selection of bacteria in the observed level is 4 times lower than the observed control culture. The cells are incubated for 16 hours in the presence of 10-10 3>cfu (colony forming units) bacterial by the cell. The level of the gene expression is determined by evaluating the quantity of transcribed gene/measuring the protein rbx-1, which is expressed by the cells and the process further comprises implementing and culturing the selected bacteria. Independent claims are also included for: (1) bacteria; (2) food composition comprising bacteria; and (3) an ensemble.</p>
申请公布号 EP1703281(A1) 申请公布日期 2006.09.20
申请号 EP20050290579 申请日期 2005.03.16
申请人 COMPAGNIE GERVAIS DANONE;INSTITUT PASTEUR 发明人 PEDRON, THIERRY;SANSONETTI, PHILIPPE;GIRARDIN, STEPHANE;BOURDET-SICARD, RAPHAELLE
分类号 G01N33/50;C12Q1/04;C12R1/225;C12R1/24 主分类号 G01N33/50
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