发明名称 Transmucosal form of administration with reduced mucosal irritation
摘要 The present invention relates to film-shaped administration forms for transmucosal administration of active substances to the human or animal body. The administration forms are characterized by an adaptation or approximation of the pH value of the base mass intended for the production of the administration form to the physiological pH value of the mucosa to which the administration form is to be applied, said base mass comprising a solvent or a mixture of solvents, at least one matrix-forming polymer and at least one active substance. The invention further comprises a process for the production of such preparations, and the use thereof as administration forms, particularly for pharmaceutical active substances, such that when the resultant administration forms are used, an irritation of the mucous membrane is reduced or even prevented.
申请公布号 US2006182786(A1) 申请公布日期 2006.08.17
申请号 US20050562422 申请日期 2005.12.27
申请人 LTS LOHMANN THERAPIE-SYSTEME AG 发明人 RADEMACHER TINA
分类号 A61K9/70;A61K9/00 主分类号 A61K9/70
代理机构 代理人
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