发明名称 |
RASAGILINE ORALLY DISINTEGRATING COMPOSITIONS |
摘要 |
This invention provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. This invention further provides a method of treating a subject afflicted with Parkinson's disease comprising administering to the subject a therapeutically effective amount of the solid pharmaceutical composition, thereby treating the subject. Finally, this invention provides a process of making such solid pharmaceutical compositions. |
申请公布号 |
WO2006057912(A3) |
申请公布日期 |
2006.08.17 |
申请号 |
WO2005US41882 |
申请日期 |
2005.11.17 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES, LTD.;TEVA PHARMACEUTICALS USA, INC;PATASHNIK, SHULAMIT;LICHT, DANIELLA;GILBERT, ADRIAN |
发明人 |
PATASHNIK, SHULAMIT;LICHT, DANIELLA;GILBERT, ADRIAN |
分类号 |
A61K31/135 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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