发明名称 ПРОИЗВОДНЫЕ БЕНЗОКСАЗЕПИНА
摘要 A compound represented by the formula [1]: wherein ring A and ring B each represent an optionally substituted benzene ring; ring C represents an optionally further substituted aromatic ring; R 1 represents a lower alkyl group optionally substituted with an optionally substituted hydroxyl group; X 1a represents a bond or optionally substituted lower alkylene; X 1b represents a bond or optionally substituted lower alkylene; X 2 represents a bond, -O- or -S-; X 3 represents a bond or an optionally substituted divalent hydrocarbon group; Y represents an optionally esterified or amidated carboxyl group, or a salt thereof. The compound of the formula [I] is safer and has more potent lipid lowering activity such as squalene synthase inhibitory activity (cholesterol lowering activity) and triglyceride lowering activity, and thus it is a compound useful as an agent for preventing or treating hyperlipemia.
申请公布号 RU2006106281(A) 申请公布日期 2006.08.10
申请号 RU20060106281 申请日期 2004.07.30
申请人 ТАКЕДА ФАРМАСЬЮТИКАЛ КОМПАНИ ЛИМИТЕД (JP) 发明人 МАРУИ Сого (JP);МИКИ Такаси (JP);МИУРА Соутароу (JP);НИСИМОТО Томоюки (JP);НАКАДА Йосихиса (JP)
分类号 C07D267/14;A61P1/18;A61P3/00;A61P3/06;A61P3/10;A61P5/14;A61P7/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P13/12;A61P19/00;A61P19/10;A61P21/00;A61P25/28;A61P43/00;C07D417/06 主分类号 C07D267/14
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