2-IMINOPYRROLIDINE DERIVATIVE

摘要

PROBLEM TO BE SOLVED: To provide a 2-iminopyrrolidine derivative having high thrombin receptor inhibitory activity, therefore serving as a compound useful as a thrombin receptor antagonist. SOLUTION: The 2-iminopyrrolidine derivative is a compound of general formula (I) or a salt thereof, which has high thrombin receptor inhibitory activity, therefore is useful as a thrombin receptor antagonist. In the general formula (I), B-ring is a benzene ring, pyridine ring or the like; R101to R103are each H, a halogen atom, 1-6C alkyl or the like; R5is H, a 1-6C alkyl, 1-6C alkoxy 1-6C alkyl or the like; R6is H, a 1-6C alkyl, 1-6C alkyloxycarbonyl or the like; Y1is a single bond; Y2is a single bond; and Ar is H. COPYRIGHT: (C)2006,JPO&NCIPI