| 摘要 |
Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, <?in-line-formulae description="In-line Formulae" end="lead"?>A-B-D-E-F-(G)<SUB>r</SUB>-(K)<SUB>s</SUB>-L, (I)<?in-line-formulae description="In-line Formulae" end="tail"?> and acid salts thereof, wherein A, B, D, E, F, G and K are alpha-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a beta-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.
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