发明名称 |
BINDUNGSPOLYMER FÜR AMIN- LIGAND-VERBINDUNGEN UND SEINE VERWENDUNG |
摘要 |
Reaction of a dialdehyde, particularly phthaldialdehyde (I), with R-Z where Z is a nucleophilic group (preferably SH) and R is polymerisable (e.g. allyl) gives a reactive thioacetal (V) which can react with an amine ligand L-NH2 to produce an isoindole (IV) which may be fluorescent. At some stage, generally before interaction with L-NH2, the R groups are polymerised, possibly leading to self-assembly of the polymer on a metal or SH-bearing surface. Such a coated surface is useful as a transducer in assays or as a binding medium e.g. for chromatography. |
申请公布号 |
DE60024432(T2) |
申请公布日期 |
2006.07.27 |
申请号 |
DE2000624432T |
申请日期 |
2000.04.25 |
申请人 |
CRANFIELD UNIVERSITY, CRANFIELD |
发明人 |
WESTON, DAVID;TURNER, PETER;CULLEN, CHARLES;PILETSKY, A.;PILETSKA, VOLODIMIRIVNA;SCHEDLER, UWE |
分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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