<p>The instant invention is based, at least in part, on the identification of a mechanism by which T-bet directly modulates Th2 cytokine production. The present invention pertains to methods of identifying agents that modulate the Tec kinase- mediated interaction of T-bet with GAT A-3, as well as methods of use therefore.</p>
申请公布号
WO2006079119(A2)
申请公布日期
2006.07.27
申请号
WO2006US02917
申请日期
2006.01.20
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;GLIMCHER, LAURIE H.;SZABO, SUSANNE J.;HWANG, EUN SOOK