| 摘要 |
<p>Methods are described for identifying immunologically reactive lymph nodes in human patients, isolating or preparing variable region recombinant proteins, identifying antigens in tumor and tissue extracts, and identifying activated germinal centers in tumor-draining and pathologically reactive-lymph nodes. The antigens and proteins may be employed as diagnostics and therapeutics for cancers and other pathological conditions. Also described are methods for screening biological samples for early tumor metastases. Stromal cell derived receptor-1/Neuroplastin gp65/55 is described as a marker of invasive potential in human tumors.</p> |
