DEVICE FOR MAGNET ASSISTED TRANSFER OF CHEMICAL COMPOUNDS INTO CELLS AND METHOD FOR MAGNET ASSISTED TRANSFER OF PROTEINS INTO CELLS

摘要

Disclosed is method for transferring a protein into a cell comprising contacting a protein to be transferred with at least one magnetic particle to form a complex comprising the protein and the magnetic particle, and contacting said complex with a cell in the presence of a suitable permanent magnetic field, thereby transferring the protein into the cell. Also disclosed is such a complex as well as to methods for making it. Further disclosed is a device for magnet assisted transfer or proteins, nucleic acids and other substances, wherein the device comprises a plurality of permanent magnets arranged adjacent to each other in a substantially gap-free and continuous arrangement that creates a substantially homogeneous magnetic surface. Furthermore, disclosed are methods, compositions and kits useful for research, diagnostics and/or therapy.