| 发明名称 |
Aryl- or heteroarylthio-phenyl cinnamide, process for its preparation and use, as well as pharmaceutical composition based thereon |
| 摘要 |
The present invention relates to novel cinnamide compounds of the general formula I, in which at least one of Ri1 to Ri5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims. These novel cinnamides are useful for inhibition of inflammations and suppression of immune response in mammals. The invention further relates to pharmaceutical compositions containing these compounds and therapeutic applications of these compounds. |
| 申请公布号 |
CZ296856(B6) |
申请公布日期 |
2006.07.12 |
| 申请号 |
CZ20010003522 |
申请日期 |
2000.04.03 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
LINK JAMES;LIU GANG;PEI ZHONGHUA;VON GELDERN THOMAS W.;WINN MARTIN;XIN ZHILI;WANG SHELDON;BOYD STEVEN A.;ZHU GUI-DONG;FREEMAN JENNIFER C.;GUNAWARDANA INDRANI W.;STAEGER MICHAEL A.;JAE HWAN-SOO;LYNCH JOHN K. |
| 分类号 |
C07C323/62;C07D243/08;A61K;A61K31/10;A61K31/165;A61K31/33;A61K31/40;A61K31/4015;A61K31/41;A61K31/417;A61K31/438;A61K31/44;A61K31/4427;A61K31/445;A61K31/4468;A61K31/451;A61K31/453;A61K31/454;A61K31/4545;A61K31/472;A61K31/496;A61K31/4965;A61K31/506;A61K31/5375;A61K31/5377;A61K31/54;A61K31/541;A61K31/55;A61K31/551;A61P;A61P29/00;A61P37/00;A61P37/06;C07C;C07C323/60;C07D;C07D205/04;C07D207/09;C07D207/12;C07D207/14;C07D207/16;C07D207/26;C07D207/27;C07D207/273;C07D209/08;C07D209/12;C07D211/20;C07D211/22;C07D211/46;C07D211/60;C07D211/62;C07D211/64;C07D211/66;C07D211/70;C07D213/40;C07D213/74;C07D213/81;C07D215/24;C07D217/02;C07D217/04;C07D217/06;C07D233/61;C07D239/42;C07D241/04;C07D241/24;C07D257/04;C07D279/12;C07D295/18;C07D295/185;C07D295/20;C07D295/205;C07D295/22;C07D295/26;C07D307/24;C07D307/52;C07D307/68;C07D317/58;C07D317/66;C07D319/18;C07D401/04;C07D401/12;C07D405/12;C07D417/12;C07D471/20;C07D487/04;C07D491/113;C07D521/00 |
主分类号 |
C07C323/62 |
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