发明名称 4-ANILINO-3-QUINOLINECARBONITRILES FOR THE TREATMENT OF CHRONIC MYELOGENOUS LEUKEMIA (CML).
摘要 <p>Compounds of formula (I) wherein n is an integer from 1-3; X is N, CH, provided that when X is N, n is 2 or 3; R is alkyl of 1 to 3 carbon atoms; R1 is 2,4-diCI, 5-OMe; 2,4-diCI; 3,4,5-triOMe; 3-CI, 5-OMe; 2-Me, 5-OMe; 2,4-di-Me; 2,4-diMe-5-OMe, 2,4-diCI, 5-OEt; R2 is alkyl of 1 to 2 carbon atoms, and pharmaceutically acceptable salts thereof are useful for the treatment of chronic myelogenous leukemia (CML).</p>
申请公布号 MXPA06004744(A) 申请公布日期 2006.07.05
申请号 MX2006PA04744 申请日期 2004.11.03
申请人 WYETH. 发明人 JENNIFER MICHELE GOLAS
分类号 A61K31/4709;A61K31/4706;A61K31/496;A61P35/00;C07D215/38;(IPC1-7):A61K31/470 主分类号 A61K31/4709
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