发明名称 |
Substituted 1-benzyl-4-substituted piperazine analogues |
摘要 |
Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).
|
申请公布号 |
US2006142301(A1) |
申请公布日期 |
2006.06.29 |
申请号 |
US20050100355 |
申请日期 |
2005.04.06 |
申请人 |
HUTCHISON ALAN J;CHENARD BERTRAND L;TARRANT JAMES G;LI GUIYING;GHOSH MANUKA;LUKE GEORGE P;PETERSON JOHN M;PRINGLE WALLACE C;O'DONNELL MARY-MARGARET E;LEE KYUNGAE;GUSTAVSON LINDA M;DOLLER DARIO |
发明人 |
HUTCHISON ALAN J.;CHENARD BERTRAND L.;TARRANT JAMES G.;LI GUIYING;GHOSH MANUKA;LUKE GEORGE P.;PETERSON JOHN M.;PRINGLE WALLACE C.;O'DONNELL MARY-MARGARET E.;LEE KYUNGAE;GUSTAVSON LINDA M.;DOLLER DARIO |
分类号 |
A61K31/496;A61K31/497;C07D213/74;C07D213/82;C07D403/02;C07D471/04;C07D487/04;C07D487/08 |
主分类号 |
A61K31/496 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|