发明名称 Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents
摘要 A compound having 5-HT<SUB>1A </SUB>receptor activity, represented by the chemical formula wherein: Ar is 2-methoxyphenyl, 1H-indol-4-yl or 2,3-dihydro-1,4-benzodioxin-5-yl; R<SUB>1 </SUB>is 2-, 3- or 4-pyridyl; R<SUB>2 </SUB>is H or C<SUB>1-6</SUB>alkyl; R<SUB>3 </SUB>is H or C<SUB>1-6</SUB>alkyl; and R<SUB>4 </SUB>is H or methyl, or an optical isomer thereof, or a pharmaceutically acceptable salt of such a compound or optical isomer. The invention also includes compositions containing such a compound, as well as methods for using a compound of the invention.
申请公布号 US7067518(B2) 申请公布日期 2006.06.27
申请号 US20030652420 申请日期 2003.08.29
申请人 WYETH 发明人 GREENBLATT LYNNE P.;KELLY MICHAEL G.;PALMER YVETTE L.
分类号 A61K31/496;C07D401/06;C07D401/12;C07D401/14;C07D405/12;C07D405/14 主分类号 A61K31/496
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