发明名称 |
COMPOUNDS, KITS AND METHODS FOR USE IN MEDICAL IMAGING |
摘要 |
FDG alternatives are provided. They consist of a two component system comprising on the one hand a building block such as glucose linked to an azide, alkyne or phosphine and on the other hand a detectable label linked to an azide, alkyne or phosphine which is the counterpart of the group linked to glucose in a Staudinger ligation reaction or a [3+2] cycloaddition reaction. It is preferred that the glucose is linked to an azide group and the detectable label is linked to a phosphine or cycloalkyne group. The detectable label is preferably a PET radionuclide label such as <SUP>18</SUP>F. |
申请公布号 |
WO2006038184(A3) |
申请公布日期 |
2006.06.22 |
申请号 |
WO2005IB53257 |
申请日期 |
2005.10.04 |
申请人 |
KONINKLIJKE PHILIPS ELECTRONICS N.V.;ROBILLARD, MARC, S.;GRUELL, HOLGER |
发明人 |
ROBILLARD, MARC, S.;GRUELL, HOLGER |
分类号 |
A61K49/00;A61K47/48;A61K51/02 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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