发明名称 |
Water soluble paclitaxel derivatives |
摘要 |
Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
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申请公布号 |
US7060724(B2) |
申请公布日期 |
2006.06.13 |
申请号 |
US20030354431 |
申请日期 |
2003.01.30 |
申请人 |
PG-TXL COMPANY, L.P. |
发明人 |
LI CHUN;WALLACE SIDNEY;YU DONG-FANG;YANG DAVID J. |
分类号 |
A01N43/02;A61K31/337;A61K41/00;A61K47/48;A61K51/04;A61K51/08;A61L31/10;A61L31/16;C07D305/00;C08G73/10 |
主分类号 |
A01N43/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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