| 发明名称 |
Method and compositions for identifying anti-hiv therapeutic compounds |
| 摘要 |
Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.
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| 申请公布号 |
US2006115815(A1) |
申请公布日期 |
2006.06.01 |
| 申请号 |
US20050511183 |
申请日期 |
2005.02.23 |
| 申请人 |
BIRKUS GABRIEL;CHEN JAMES M;CHEN XIAOWU;CIHLAR TOMAS;EISENBERG EUGENE J;HATADA MARCOS;HE GONG-XI;KIM CHOUNG U;LEE WILLIAM A;MCDERMOTT MARTIN J;SWAMINATHAN SUNDARAMOORTHI |
发明人 |
BIRKUS GABRIEL;CHEN JAMES M.;CHEN XIAOWU;CIHLAR TOMAS;EISENBERG EUGENE J.;HATADA MARCOS;HE GONG-XI;KIM CHOUNG U.;LEE WILLIAM A.;MCDERMOTT MARTIN J.;SWAMINATHAN SUNDARAMOORTHI |
| 分类号 |
C12N9/99;C12Q1/70;A61K31/4155;A61K31/66;A61K31/665;A61K31/675;A61P31/18;A61P43/00;C07D213/75;C07D213/85;C07D231/12;C07D231/20;C07D233/42;C07D239/48;C07D239/80;C07D243/04;C07D265/18;C07D307/68;C07D401/06;C07D403/06;C07D471/14;C07D491/04;C07F;C07F9/02;C07F9/38;C07F9/40;C07F9/44;C07F9/58;C07F9/62;C07F9/645;C07F9/6506;C07F9/6509;C07F9/6512;C07F9/653;C07F9/6533;C07F9/655;C07F9/6558;C07F9/6561;C07F9/6584;C12N9/16;C12Q1/18;C12Q1/37;C12Q1/44;G01N33/04;G01N33/50 |
主分类号 |
C12N9/99 |
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