ACYCLIC NUCLEOSIDE DERIVATIVES

摘要

COMPOUNDS OF THE FORMULA I WHERE ONE OF R1 AND R2 IS -C(O)CH(CH(CH3)2)NH2 OR, -C(O)CH(CH(CH3)CH2CH3)NH2; THE OTHER OF R1 AND R2 IS -C(=O)C3-C21 SATURATED OR MONOUNSATURATED, OPTIONALLY SUBSTITUTED ALKYL; AND R3 IS OH OR H; AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE UTILITY AS ENHANCED BIOAVAILABILITY ANTIVIRALS AGAINST HERPES AND RETROVIRAL INFECTIONS.