USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMORS AND NECROSES

摘要

The invention relates to the use of metal complexes containing perfluoroalkyl, comprising a critical micelle formation concentration <10-3 mol/l, a hydrodynamic micelle dynameter of (2Rh) >1 nm and a proton relaxivity in plasma (R1) > 101/mmol.s, as contrast agents in MR imaging for the representation of plague, lymph node, infracted and necrotic tissue and for independent representation of necrotic tissue and tumoural tissue.