ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS
摘要
Provided herein are compounds of formula (I) wherein R1-4, n and Ar are as defined in claim 1, and their pharmaceutical compositions. These compounds are tryptase inhibitors and may be used in the treatment of e.g. asthma and inflammatory diseases.
申请公布号
YU87202(A)
申请公布日期
2006.05.25
申请号
YU2002P000872
申请日期
2001.04.27
申请人
AVENTIS PHARMACEUTICALS INC.
发明人
ASTLES, PETER C.;EASTWOOD, PAUL R.;HOUILLE, OLIVIER;LEVELL, JULIAN;PAULS, HEINZ;CZEKAJ, MARK;LIANG, GUYAN;GONG, YONG;PRIBISH, JAMES;NEUENSCHWANDER, KENT