| 发明名称 |
Oligonucleotides having alkylphosphonate linkages and methods for their preparation |
| 摘要 |
The present invention provides alkylphosphonate dimers and oligonucleotides prepared therefrom. The invention further provides novel methods for the preparation of these alkylphosphonate dimers. Methods for the preparation of substantially diastereomerically pure alkylphosphonate dimers are also provided.
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| 申请公布号 |
US7049432(B2) |
申请公布日期 |
2006.05.23 |
| 申请号 |
US20020163439 |
申请日期 |
2002.06.04 |
| 申请人 |
MCGILL UNIVERSITY |
发明人 |
MANOHARAN MUTHIAH;JUST GEORGE;GUZAEV ANDREI;ROLAND ARLENE;WANG JIANCHAO;JUNG MICHAEL E. |
| 分类号 |
C07H21/02;C07H19/04;C07H21/00;C07H21/04 |
主分类号 |
C07H21/02 |
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