Aminoalcohol derivatives

摘要

The present invention relates to a compound formula [I]: wherein Y is bond, -O-(CH₂)_n- (in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R¹ is hydrogen, lower alkyl, etc., R² is hydrogen or an amino protective group, R³ is hydrogen or lower alkyl, R⁴ is hydrogen or lower alkyl, R⁵ and R⁸ are each independently hydrogen, halogen, hydroxy, lower alkyl, etc., R⁶ is hydrogen, lower alkyl, etc., R⁹ is hydrogen or lower alkyl, and i is 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.