发明名称 |
Method of improving bioavailability of orally administered drugs, a method of screening for enhancers of such bioavailability and novel pharmaceutical compositions for oral delivery of drugs |
摘要 |
A method for increasing the systemic exposure of cells selected from tumor cells and normal cells to an orally administered pharmaceutically active compound, wherein a bioenhancer comprising an inhibitor of BCRP is orally administered concomitantly with said orally administered pharmaceutically active compound, and in which method the inhibitor is administered simultaneously with the pharmaceutical compound.
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申请公布号 |
US7030132(B2) |
申请公布日期 |
2006.04.18 |
申请号 |
US20010988285 |
申请日期 |
2001.11.19 |
申请人 |
CANCER RESEARCH VENTURES LIMITED |
发明人 |
SCHELLENS JOHANNES HENRICUS MATTHIAS;SCHINKEL ALFRED HERMANUS |
分类号 |
A61K31/44;A61K31/56;A61K45/06;A61P35/00 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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