发明名称 |
METHODS OF SCREENING COMPOSITIONS FOR G PROTEIN-COUPLED RECEPTOR DESENSITIZATION INHIBITORY ACTIVITY |
摘要 |
The methods of the present invention allow the screening of a test composition for non-receptor-specific GPCR desensitization inhibitory activity. The methods involve screening a test composition for an indication of GPCR desensitization inhibitory activity against two or more GPCRs that are different from each other. When there is an indication that a particular test composition has GPCR desensitization inhibitory activity with respect to each of the two or more GPCRs that are different from one another, then, according to the present invention, there is an indication that the test composition has non-receptor-specific GPCR desensitization inhibitory activity. |
申请公布号 |
WO2005012876(A3) |
申请公布日期 |
2006.04.13 |
申请号 |
WO2004US24572 |
申请日期 |
2004.07.30 |
申请人 |
NORAK BIOSCIENCES, INC.;OAKLEY, ROBERT, H. |
发明人 |
OAKLEY, ROBERT, H. |
分类号 |
C07K14/705;C07K19/00;C12N15/62;C12Q1/68;G01N;G01N33/50;G01N33/53;G01N33/567 |
主分类号 |
C07K14/705 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|