发明名称 |
POLYPEPTIDE EXPRESSED IN THE HORNY LAYER OF EPIDERMIS AND USE THEREOF |
摘要 |
<p>The present invention relates to a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a purified natural or synthetic epidermis-specific polypeptide which is involved in horny layer cell cohesion. The invention also relates to a cosmetic or pharmaceutical composition comprising a mixture of polypeptides derived from the proteolysis of the purified polypeptide of the present invention. The present invention further relates to a method for strengthening horny layer cell cohesion which comprises applying the cosmetic or pharmaceutical composition of the present invention to the skin. Finally, the present invention relates to a method for reducing horny layer cell cohesion, and thereby promoting exfoliation, wherein said method comprises applying to the skin a cosmetic or pharmaceutical composition comprising an effective amount of at least one protease active on the polypeptide of the present invention.</p> |
申请公布号 |
EP0972042(B1) |
申请公布日期 |
2006.04.12 |
申请号 |
EP19980920561 |
申请日期 |
1998.03.27 |
申请人 |
L'OREAL |
发明人 |
SERRE, GUY, BRUNO, RENE;SIMON, MICHEL;WEBER-VIVAT, MARINA |
分类号 |
A61K8/72;C12N15/12;A61K8/00;A61K8/04;A61K8/11;A61K8/60;A61K8/64;A61K8/66;A61K8/96;A61K8/98;A61K38/00;A61K38/17;A61P17/00;A61P43/00;A61Q1/00;A61Q1/12;A61Q5/02;A61Q5/04;A61Q5/10;A61Q9/04;A61Q11/00;A61Q17/02;A61Q19/00;C07K14/47;C07K16/18;C12N15/09;C12P21/02;C12P21/08 |
主分类号 |
A61K8/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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