发明名称 Cysteine protease inhibitors with 2-cyano-4-amino-pyrimidine structure and cathepsin K inhibitory activity for the treatment of inflammations and other diseases
摘要 The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof (I), wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g., various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
申请公布号 US2006074092(A1) 申请公布日期 2006.04.06
申请号 US20050291007 申请日期 2005.11.30
申请人 发明人 ALTMANN EVA;HAYAKAWA KENJI;IWASAKI GENJI
分类号 C07D239/42;A61K31/505;A61P1/02;A61P9/10;A61P11/00;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P21/04;A61P29/00;A61P33/00;A61P33/06;A61P33/12;A61P35/00;A61P37/02;A61P43/00;C07D401/12;C07D403/12 主分类号 C07D239/42
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