INDOLE ACETIC ACIDS EXHIBITING CRTH2 RECEPTOR ANTAGONISM AND USES THEREOF
摘要
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.
申请公布号
WO2006034419(A2)
申请公布日期
2006.03.30
申请号
WO2005US34029
申请日期
2005.09.21
申请人
ATHERSYS, INC.;BENNANI, YOUSSEF L.;TUMEY, LAWRENCE N.;GLEASON, ELIZABETH ANN;ROBARGE, MICHAEL JOSEPH
发明人
BENNANI, YOUSSEF L.;TUMEY, LAWRENCE N.;GLEASON, ELIZABETH ANN;ROBARGE, MICHAEL JOSEPH