| 发明名称 |
AMINOTHIAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES |
| 摘要 |
Compounds of formula (I) and pharmaceutically acceptable salts thereof. As used in formula (I), and throughout the specification, the symbols have the following meanings: R1 and R2 are independently hydrogen, fluorine or alkyl; R3 is aryl or heteroaryl. The compounds of formula (I) are protein kinase inhibitors and are useful in the treatment and prevention of proliferative diseases, for example cancer, inflammation and arthritis.
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| 申请公布号 |
CA2309551(C) |
申请公布日期 |
2006.03.28 |
| 申请号 |
CA19982309551 |
申请日期 |
1998.11.02 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
KIM, KYOUNG S.;HAN, WEN-CHING;HUNT, JOHN T.;WEBSTER, KEVIN;CAI, ZHEN-WEI;POSS, MICHAEL A.;MISRA, RAJ N.;KIMBALL, S. DAVID;RAWLINS, DAVID B. |
| 分类号 |
C07D277/20;C07D417/12;A61K31/426;A61K31/427;A61K31/433;A61K31/4439;A61K31/454;A61K31/497;A61K31/506;A61P1/04;A61P9/00;A61P9/10;A61P9/14;A61P17/02;A61P17/06;A61P19/02;A61P21/00;A61P25/16;A61P25/28;A61P29/00;A61P31/10;A61P31/12;A61P31/18;A61P35/00;A61P37/06;A61P43/00;C07D263/00;C07D277/00;C07D277/42;C07D277/44;C07D277/54;C07D417/14 |
主分类号 |
C07D277/20 |
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