发明名称 |
TEAR DYNAMICS MEASURED WITH OPTICAL COHERENCE TOMOGRAPHY |
摘要 |
<p>A system and method are provided for measuring the thickness of a tear film layer (208) and the heights of tear menisci (210, 212) around upper and lower eyelids of an eye. A plurality of images are acquired between consecutive blinks the eye using optical coherence tomography (OCT). The images depict the tear film layer (208) and tear menisci (210, 212) as distinct from the cornea of the eye. In an embodiment, a plurality of reflectivity profiles (602) from an OCT image are aligned and averaged. The difference between a first peak (608) and a second peak (610) of the average reflectivity profile is measured to determine the thickness of the tear film layer. The heights of the upper meniscus (210) and the lower meniscus (212) can also be measured from the same OCT image. In an embodiment, thickness measurements from the plurality of OCT images are combined. The measurements can be used to diagnose tear disorders, analyze treatments of dry eye and evaluate artificial tears.</p> |
申请公布号 |
WO2006031909(A2) |
申请公布日期 |
2006.03.23 |
申请号 |
WO2005US32781 |
申请日期 |
2005.09.14 |
申请人 |
UNIVERSITY OF ROCHESTER MEDICAL CENTER;WANG, M.D., PH.D., JIANHUA |
发明人 |
WANG, M.D., PH.D., JIANHUA |
分类号 |
A61B3/14;A61B3/10 |
主分类号 |
A61B3/14 |
代理机构 |
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