发明名称 |
Thrombotic episode risk assays using oxidized phospholipids |
摘要 |
An assay to assess thrombotic risk in which oxidized lipids comprising phospholipids are utilized as a membrane source in a clotting assay and the results compared to an assay in which unoxidized phospholipid is used as a membrane source in the presence and absence of activated protein C ("APC"). The assay can monitor for the presence of antibodies in the patient which interfere specifically with the anticoagulant function of APC in an oxidation dependent or independent manner. This can indicate the propensity of the patient to experience episodes of vein thrombosis or arterial thrombosis.
|
申请公布号 |
US7011956(B1) |
申请公布日期 |
2006.03.14 |
申请号 |
US20020088021 |
申请日期 |
2002.07.26 |
申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
ESMON NAOMI L.;JAMILABADI OMID SAFA |
分类号 |
C12Q1/56;G01N33/86;G01N33/92 |
主分类号 |
C12Q1/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|